Best for Alpha MD
Men comparing lower-friction telehealth TRT subscriptions with more involved clinic models.
Best for Defy Medical
Experienced users who want physician-led TRT or HRT with access to peptides, NAD+, and advanced hormone protocols.
Biggest difference
Remote-friendly vs Remote-friendly access model.
Alpha MD: Alpha MD shows a visible starting price of $129 per month, but deeper pricing detail is not fully public on the reviewed pages. Defy Medical: Defy Medical shows a visible starting price of $250 per month, but deeper pricing detail is not fully public on the reviewed pages.
Alpha MD: Membership structure can make the first visible price look cleaner than the full long-term cost.
Defy Medical: Pricing across the full service menu can be complex — initial consult and lab costs are separate from ongoing therapy costs.
Alpha MD: A mandatory consult step was not clearly listed on the reviewed homepage.
Defy Medical: The public flow suggests clinician review or consultation before treatment begins.
Alpha MD: Lab testing is signaled in the visible care model.
Defy Medical: Lab testing is signaled in the visible care model.
Alpha MD: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling.
Defy Medical: No clear cancellation or refund language was surfaced on the reviewed official pages.
Alpha MD: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.
Defy Medical: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.
Alpha MD: Medication changes, shipping, or premium tiers may still change the final bill.
Defy Medical: Medication changes, shipping, or premium tiers may still change the final bill.
Last updated
Apr 28, 2026
Providers analyzed
2
Price range
$129 vs $250-$300
Methodology
How we collect data
Disclosure
Affiliate relationships
online TRT clinic focused on affordable testosterone therapy and men’s hormone management
Alpha MD is a online TRT clinic focused on affordable testosterone therapy and men’s hormone management.
Starting price
$129
per month
Service availability
Men comparing lower-friction telehealth TRT subscriptions with more involved clinic models.
Users who want a direct online testosterone benchmark in the directory.
A physician-led hormone and longevity clinic with one of the broadest publicly documented service menus in the TRT and peptide space.
Defy Medical is a Tampa-based integrative health clinic with strong national telehealth reach specializing in TRT, HRT, peptide therapy, NAD+ therapy, and comprehensive hormone optimization.
Starting price
$250
per month
Service availability
Experienced users who want physician-led TRT or HRT with access to peptides, NAD+, and advanced hormone protocols.
Patients comfortable navigating a clinical, protocol-driven model rather than a consumer-friendly membership app.
| Signal | Alpha MD | Defy Medical |
|---|---|---|
| TRT price | $129 | $250 |
| Price range | $129 | $250-$300 |
| Care model | Remote-friendly | Remote-friendly |
| Membership model | Membership required | No membership required |
| Availability | 21 states + telehealth | 1 states + telehealth |
| Transparency score | 5/5 | 5/5 |
| Limitations | Membership structure can make the first visible price look cleaner than the full long-term cost. | Pricing across the full service menu can be complex — initial consult and lab costs are separate from ongoing therapy costs. |
Best for price
Alpha MD currently shows the lower visible trt price anchor.
Best for convenience
Alpha MD looks easier to use for shoppers prioritizing access and lower-friction logistics.
Best for service variety
Defy Medical currently offers the broader service stack around this category.
Best for beginners
Alpha MD looks friendlier for first-time shoppers who want simpler onboarding.
Choose Alpha MD if your goal is the stronger overall mix of price clarity and service fit in trt. Choose Defy Medical if its access model or care structure is closer to how you actually want to buy this treatment.
Specific to TRT programs — the service being compared here.
Cheapest likely scenario
Alpha MD
Alpha MD currently shows the lower visible trt price anchor, but the real bill still depends on labs, consults, and membership rules.
Fastest access
Alpha MD
Alpha MD looks better for low-friction access if you care most about telehealth and a simpler booking path.
Transparent pricing
Alpha MD
Alpha MD currently publishes the cleaner pricing trail for trt.
More medically supervised
Verify both directly
Both providers need direct verification on clinician review, labs, and follow-up cadence.
Alpha MD currently shows the lower visible trt price anchor, though the real comparison still depends on membership, labs, and consult structure.
Alpha MD currently looks stronger on the service-specific comparison because of its current blend of pricing, access model, and overall provider fit.
Because buyers often want a narrower answer than a full-provider comparison when they are only shopping one treatment category.
Full provider comparison
Zoom back out to the all-services comparison page.
Alpha MD TRT
Open the provider's service-specific review.
Defy Medical TRT
Open the provider's service-specific review.
TRT guide
Compare the broader service category.
TRT calculator
Model likely spend for this category.
SynergenX TRT
Compare another provider in this treatment category.
Regenics TRT
Compare another provider in this treatment category.
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Methodology and disclaimer
This service comparison page is generated from provider overlap, current price anchors, convenience signals, and treatment-specific fit data. It is designed to be useful for category research, not medical decision-making.
Informational only. Longevity Costs publishes provider research, public pricing context, and comparison summaries for informational purposes only. The site is not a medical provider, clinic, pharmacy, or emergency service. Nothing on this page is medical advice, diagnosis, treatment guidance, or a claim that a therapy is proven, guaranteed, or appropriate for you. Consult a licensed medical professional before starting or changing any therapy.
Source
Public provider websites, rate sheets, and documented offers.
Verification
Verify final pricing directly with the provider before booking.
Cadence
Data is reviewed and updated on a rolling basis.
Sources
