Defy Medical vs Upgrade Labs for Wellness Labs (2026): Cost & Which Wins

Best for Defy Medical

Experienced users who want physician-led TRT or HRT with access to peptides, NAD+, and advanced hormone protocols.

Best for Upgrade Labs

Users who want a biohacking-club alternative to lab-only memberships.

Biggest difference

Remote-friendly vs In-person access model.

Decision helper

Defy Medical: Defy Medical shows a visible starting price of $250 per month, but deeper pricing detail is not fully public on the reviewed pages. Upgrade Labs: Upgrade Labs shows a visible starting price of $199 per package, but deeper pricing detail is not fully public on the reviewed pages.

Notable limitations

Defy Medical: Pricing across the full service menu can be complex — initial consult and lab costs are separate from ongoing therapy costs.

Upgrade Labs: Membership structure can make the first visible price look cleaner than the full long-term cost.

Publicly verified care model notes

Defy Medical: The public flow suggests clinician review or consultation before treatment begins.

Upgrade Labs: A mandatory consult step was not clearly listed on the reviewed homepage.

Defy Medical: Lab testing is signaled in the visible care model.

Upgrade Labs: Lab requirements or repeat monitoring details were not clearly listed on the reviewed homepage.

Defy Medical: No clear cancellation or refund language was surfaced on the reviewed official pages.

Upgrade Labs: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling.

Transparency notes

Defy Medical: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

Upgrade Labs: Payment, privacy, or billing-policy pages were reviewed, but insurance, HSA, or FSA handling should still be confirmed directly.

Defy Medical: Medication changes, shipping, or premium tiers may still change the final bill.

Upgrade Labs: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Data snapshot — pricing sourced from public provider rates

Last updated

Apr 28, 2026

Providers analyzed

Price range

$250-$300 vs $199

Methodology

How we collect data

Disclosure

Affiliate relationships

Defy Medical

Specialist clinic

A physician-led hormone and longevity clinic with one of the broadest publicly documented service menus in the TRT and peptide space.

Defy Medical is a Tampa-based integrative health clinic with strong national telehealth reach specializing in TRT, HRT, peptide therapy, NAD+ therapy, and comprehensive hormone optimization.

NAD TherapyTRTHRTPeptides

Starting price

$250

per month

Service availability

Telehealth available

Labs included

Tampa, FL

Experienced users who want physician-led TRT or HRT with access to peptides, NAD+, and advanced hormone protocols.

Patients comfortable navigating a clinical, protocol-driven model rather than a consumer-friendly membership app.

See Pricing Details Check Provider

Upgrade Labs

Official website reviewed

biohacking and performance clinic brand with longevity-tech services and memberships

Upgrade Labs is a biohacking and performance clinic brand with longevity-tech services and memberships.

Wellness LabsDEXA ImagingSleep OptimizationLongevity Memberships

Starting price

$199

per package

Service availability

Clinic-led access

Labs may be separate

Santa Monica, CA

Users who want a biohacking-club alternative to lab-only memberships.

Shoppers comparing tech-forward wellness clubs in major metros.

See Pricing Details Check Provider

Signal	Defy Medical	Upgrade Labs
Wellness Labs price	$250	$199
Price range	$250-$300	$199
Care model	Remote-friendly	In-person
Membership model	No membership required	Membership required
Availability	1 states + telehealth	Santa Monica, CA, Austin, TX
Transparency score	4/5	3/5
Limitations	Pricing across the full service menu can be complex — initial consult and lab costs are separate from ongoing therapy costs.	Membership structure can make the first visible price look cleaner than the full long-term cost.

Winner by category

Best for price

Upgrade Labs currently shows the lower visible wellness labs price anchor.

Best for convenience

Defy Medical looks easier to use for shoppers prioritizing access and lower-friction logistics.

Best for service variety

Defy Medical currently offers the broader service stack around this category.

Best for beginners

Defy Medical looks friendlier for first-time shoppers who want simpler onboarding.

Which should you choose?

Choose Upgrade Labs if your goal is the stronger overall mix of price clarity and service fit in wellness labs. Choose Defy Medical if its access model or care structure is closer to how you actually want to buy this treatment.

Questions to ask before choosing

Specific to Wellness Labs programs — the service being compared here.

1Is a physician order required, or can I order panels directly?
2Are results reviewed with a clinician, or returned raw with no interpretation?
3What is the cost per panel, and is a membership or bundle more cost-effective?
4Can I use insurance or my HSA/FSA to pay for any of these tests?

Shopper intent shortcuts

Cheapest likely scenario

Upgrade Labs

Upgrade Labs currently shows the lower visible wellness labs price anchor, but the real bill still depends on labs, consults, and membership rules.

Fastest access

Defy Medical

Defy Medical looks better for low-friction access if you care most about telehealth and a simpler booking path.

Transparent pricing

Defy Medical

Defy Medical currently publishes the cleaner pricing trail for wellness labs.

More medically supervised

Defy Medical

Defy Medical signals a stronger lab-driven workflow on the current public data.

FAQ

Wellness Labs comparison questions

Which provider is cheaper for wellness labs: Defy Medical or Upgrade Labs?

Upgrade Labs currently shows the lower visible wellness labs price anchor, though the real comparison still depends on membership, labs, and consult structure.

Which provider looks stronger for wellness labs overall?

Upgrade Labs currently looks stronger on the service-specific comparison because of its current blend of pricing, access model, and overall provider fit.

Why break this out into a wellness labs comparison page?

Because buyers often want a narrower answer than a full-provider comparison when they are only shopping one treatment category.

Related paths

Next comparison clicks

Full provider comparison

Zoom back out to the all-services comparison page.

Defy Medical Wellness Labs

Open the provider's service-specific review.

Upgrade Labs Wellness Labs

Open the provider's service-specific review.

Wellness Labs guide

Compare the broader service category.

Wellness Labs calculator

Model likely spend for this category.

Next Health Wellness Labs

Compare another provider in this treatment category.

SynergenX Wellness Labs

Compare another provider in this treatment category.

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Function Health Membership Cost: What You Are Actually Paying For

Read related editorial context.

Methodology and disclaimer

Updated Apr 28, 2026

This service comparison page is generated from provider overlap, current price anchors, convenience signals, and treatment-specific fit data. It is designed to be useful for category research, not medical decision-making.

Informational only. Longevity Costs publishes provider research, public pricing context, and comparison summaries for informational purposes only. The site is not a medical provider, clinic, pharmacy, or emergency service. Nothing on this page is medical advice, diagnosis, treatment guidance, or a claim that a therapy is proven, guaranteed, or appropriate for you. Consult a licensed medical professional before starting or changing any therapy.

Source

Public provider websites, rate sheets, and documented offers.

Verification

Verify final pricing directly with the provider before booking.

Cadence

Data is reviewed and updated on a rolling basis.

Sources

Defy Medical homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

Sources

Upgrade Labs homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

Upgrade Labs contact page

Checked 2026-05-06 · Confidence 64%

Contact or support availability reviewed from official pages.

Upgrade Labs faq page

Checked 2026-05-06 · Confidence 56%

FAQ reviewed for support, cancellation, and policy language.

Upgrade Labs terms page

Checked 2026-05-06 · Confidence 62%

Terms or billing-policy language reviewed for cancellation clues.

Upgrade Labs privacy page

Checked 2026-05-06 · Confidence 50%

Privacy or billing-policy page reviewed for support and payment context.

Publicly verified care model notes

Defy Medical: The public flow suggests clinician review or consultation before treatment begins.

Upgrade Labs: A mandatory consult step was not clearly listed on the reviewed homepage.

Defy Medical: Lab testing is signaled in the visible care model.

Upgrade Labs: Lab requirements or repeat monitoring details were not clearly listed on the reviewed homepage.

Defy Medical: No clear cancellation or refund language was surfaced on the reviewed official pages.

Upgrade Labs: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling.

Transparency notes

Defy Medical: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

Upgrade Labs: Payment, privacy, or billing-policy pages were reviewed, but insurance, HSA, or FSA handling should still be confirmed directly.

Defy Medical: Medication changes, shipping, or premium tiers may still change the final bill.

Upgrade Labs: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Signal

Defy Medical

Upgrade Labs

Wellness Labs price

$250

$199

Price range

$250-$300

$199

Care model

Remote-friendly

In-person

Membership model

No membership required

Membership required

Availability

1 states + telehealth

Santa Monica, CA, Austin, TX

Transparency score

4/5

3/5

Limitations

Pricing across the full service menu can be complex — initial consult and lab costs are separate from ongoing therapy costs.

Membership structure can make the first visible price look cleaner than the full long-term cost.

Winner by category

Best for price

Upgrade Labs currently shows the lower visible wellness labs price anchor.

Best for convenience

Defy Medical looks easier to use for shoppers prioritizing access and lower-friction logistics.

Best for service variety

Defy Medical currently offers the broader service stack around this category.

Best for beginners

Defy Medical looks friendlier for first-time shoppers who want simpler onboarding.

Questions to ask before choosing

Specific to Wellness Labs programs — the service being compared here.

1Is a physician order required, or can I order panels directly?

2Are results reviewed with a clinician, or returned raw with no interpretation?

3What is the cost per panel, and is a membership or bundle more cost-effective?

4Can I use insurance or my HSA/FSA to pay for any of these tests?

Shopper intent shortcuts

Cheapest likely scenario

Upgrade Labs

Upgrade Labs currently shows the lower visible wellness labs price anchor, but the real bill still depends on labs, consults, and membership rules.

Fastest access

Defy Medical

Defy Medical looks better for low-friction access if you care most about telehealth and a simpler booking path.

Transparent pricing

Defy Medical

Defy Medical currently publishes the cleaner pricing trail for wellness labs.

More medically supervised

Defy Medical

Defy Medical signals a stronger lab-driven workflow on the current public data.