Life Extension: Life Extension has one of the largest direct-to-consumer longevity supplement catalogs with public pricing on all products.
One Medical: One Medical is Amazon-owned, giving it brand recognition, technology infrastructure, and scale that independent concierge practices cannot match.
Life Extension: Life Extension sells individual supplements starting under $20, with popular longevity stacks running $40–$80/month. Lab test panels range from $35 to over $200 depending on the panel. A $0 annual member program provides discounts of 5–30% on products.
One Medical: One Medical charges $199/year for membership, which includes 24/7 virtual care access and in-person visits at One Medical clinics. Amazon Prime members have a discounted or bundled access path. Lab costs, specialist referrals, and prescriptions are billed separately or through insurance.
Life Extension: Free annual membership that provides discount pricing on supplements and lab tests. No mandatory subscription.
One Medical: $199/year membership. Corporate plans and Amazon Prime bundles may alter the pricing.
Life Extension: No physician consult is required for supplement purchases. Lab tests are ordered directly without clinician gating.
One Medical: No-cost same-day or next-day appointments with primary care physicians at One Medical clinics. Virtual consults available 24/7.