Provider comparison1 shared servicesData confidence 65%

ProLon vs Signos

ProLon and Signos are close enough on paper that users should focus on transparency, membership friction, and care-access differences before choosing a next click. This page compares pricing, services, telehealth support, labs, and overall provider fit so it works as a real decision page instead of a thin comparison permutation.

Quick verdict

ProLon is the stronger current profile

ProLon has the stronger current profile for this comparison. Open it first — then verify pricing, labs, and cancellation terms directly before deciding.

ProLon: $189/per packageSignos: $199/per monthUpdated: Apr 28, 2026

Open ProLon Open Signos Get matched

Best for ProLon

Users exploring fasting-mimicking diet protocols as part of a broader longevity or cellular health strategy.

Best for Signos

Users comparing app-driven CGM programs that tie glucose data directly into weight or metabolic change goals.

Biggest difference

ProLon and Signos are close enough on paper that users should focus on transparency, membership friction, and care-access differences before choosing a next click.

Price transparency: 3/5 vs 3/5. Availability: In-person vs In-person.

Market median

$149

13 researched providers in this treatment path.

Transparent pricing rate

100%

of researched providers publish a usable price anchor.

Telehealth rate

77%

support remote access in this comparison set.

Data snapshot — pricing sourced from public provider rates

Last updated

Apr 28, 2026

Providers analyzed

Price range

$189 vs $199

Methodology

How we collect data

Disclosure

Affiliate relationships

ProLon

Official website reviewed

fasting mimicking diet program developed by longevity scientist Valter Longo, offering 5-day meal kits designed to trigger autophagy and cellular renewal while avoiding complete fasting

ProLon is a fasting mimicking diet program developed by longevity scientist Valter Longo, offering 5-day meal kits designed to trigger autophagy and cellular renewal while avoiding complete fasting.

Longevity SupplementsMetabolic HealthSupplements

Starting price

$189

per package

Service availability

Clinic-led access

Labs may be separate

National direct-to-consumer

Users exploring fasting-mimicking diet protocols as part of a broader longevity or cellular health strategy.

Visitors comparing diet-based longevity interventions against supplement stacks and IV therapy programs.

See Pricing Details Check Provider

Signos

Official website reviewed

app-led metabolic health program centered on CGM-guided behavior change and ongoing subscription access

Signos is a app-led metabolic health program centered on CGM-guided behavior change and ongoing subscription access.

CGM DiagnosticsMetabolic HealthLongevity Memberships

Starting price

$199

per month

Service availability

Clinic-led access

Labs may be separate

National digital platform

Users comparing app-driven CGM programs that tie glucose data directly into weight or metabolic change goals.

Visitors who want a Signos-specific comparison page alongside Levels and NutriSense.

See Pricing Details Check Provider

Signal	ProLon	Signos
Starting price	$189 per package	$199 per month
Price range	$189	$199
Services offered	Longevity Supplements, Metabolic Health, Supplements	CGM Diagnostics, Metabolic Health, Longevity Memberships
Online vs in-person	In-person	In-person
Best for	Users exploring fasting-mimicking diet protocols as part of a broader longevity or cellular health strategy.	Users comparing app-driven CGM programs that tie glucose data directly into weight or metabolic change goals.
Membership availability	No membership required	Membership required
Locations or availability	National direct-to-consumer	National digital platform
Transparency score	3/5	3/5
Limitations	Some final pricing still depends on consult review, location, or service customization.	Membership structure can make the first visible price look cleaner than the full long-term cost.

Hidden fees to watch for

Published starting prices rarely include all costs. These are the most common fee gaps buyers miss when comparing ProLon and Signos.

ProLon

Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Signos

Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Lab monitoring (both)

Most telehealth programs do not include lab work in the monthly fee. Expect $75–$150 per panel, required 2–4× per year for any hormone or TRT program.

Initiation and intake fees

Some providers charge a one-time intake fee ($50–$199) on top of the first monthly payment. This is not always visible on the pricing page.

ProLon pros and cons

Official site clearly positions ProLon around longevity supplements, metabolic health and broader longevity support.

Physical or concierge delivery model adds useful contrast against telehealth-first providers already in the directory.

Published service framing is strong enough to support provider, comparison, and location pages.

Some final pricing still depends on consult review, location, or service customization.

Signos pros and cons

Official site clearly positions Signos around cgm diagnostics, metabolic health and broader longevity support.

Physical or concierge delivery model adds useful contrast against telehealth-first providers already in the directory.

Published service framing is strong enough to support provider, comparison, and location pages.

Membership structure can make the first visible price look cleaner than the full long-term cost.

Notable limitations

ProLon: Some final pricing still depends on consult review, location, or service customization.

Signos: Membership structure can make the first visible price look cleaner than the full long-term cost.

Decision helper

ProLon has the cleaner current edge if you care most about transparency and a broader decision trail.

Signos may still fit better if its geography, clinic structure, or narrower service mix is closer to what you want.

Both providers share Metabolic Health — compare pricing models for those specific services before deciding.

Best for

ProLon

Users exploring fasting-mimicking diet protocols as part of a broader longevity or cellular health strategy.

Signos

Users comparing app-driven CGM programs that tie glucose data directly into weight or metabolic change goals.

Winner by category

Best for price

ProLon currently shows the cleaner lower-cost starting point.

Best for convenience

ProLon currently looks easier to use for remote or low-friction access.

Best for service variety

ProLon offers the broader menu for users who may stack more than one treatment path.

Most cautious beginner

Start with ProLon if you want the simpler onboarding path before you compare the more complex alternative.

Best for beginners

ProLon looks friendlier for first-time shoppers who want simpler onboarding and less membership friction.

Questions to ask before choosing

These are specific to Metabolic Health programs — the primary service overlap between ProLon and Signos.

1What is included in the base membership price versus billed additionally?
2How frequently are labs and provider consultations included, and at what cadence?
3What is the cancellation policy if the program does not meet my expectations?
4How does the provider handle monitoring if my biomarkers fall outside the target range?

Which should you choose?

ProLon currently has the better comparison profile for this page, but that is not the same as a universal winner. Use ProLon as the first profile to open if you care most about clearer pricing and broader comparison detail. Use Signos first if its access model or service style is closer to how you actually want to buy care.

Hidden-cost risk and cancellation

ProLon: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Signos: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

ProLon: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling.

Signos: Cancellation or pause terms were not clearly listed on the reviewed official pages and should be checked directly.

Intent-based shortcuts

I want the cheapest option

ProLon

ProLon currently shows the lower visible price anchor, but verify whether labs, medication, or membership fees sit outside the headline number.

I want fastest access

ProLon

ProLon looks easier to start quickly based on telehealth access, lower friction, or a simpler booking path.

I want stronger medical oversight

Verify both directly

Both providers need direct verification on clinician review, lab cadence, and how much oversight is actually included.

I want transparent pricing

ProLon

ProLon currently publishes the cleaner pricing trail, but both still deserve a final check on renewals and add-on fees.

I want local or in-person care

ProLon

Use clinic footprint, state coverage, and intake model together here - local care usually changes convenience, follow-up cadence, and total cost.

Publicly verified differences

ProLon: Users exploring fasting-mimicking diet protocols as part of a broader longevity or cellular health strategy.

Signos: Users comparing app-driven CGM programs that tie glucose data directly into weight or metabolic change goals.

ProLon: ProLon shows a visible starting price of $189 per package, but deeper pricing detail is not fully public on the reviewed pages.

Signos: Signos shows a visible starting price of $199 per month, but deeper pricing detail is not fully public on the reviewed pages.

ProLon: No mandatory membership fee was clearly listed on the reviewed homepage.

Signos: A recurring membership or subscription appears to be part of the offer, but the exact public fee still needs manual review.

ProLon: A mandatory consult step was not clearly listed on the reviewed homepage.

Signos: A mandatory consult step was not clearly listed on the reviewed homepage.

Transparency and policy notes

ProLon: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

Signos: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

ProLon: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Signos: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Some outbound buttons may use affiliate relationships. Rankings are driven by editorial methodology and provider data, not by paid placement. This directory is for informational and research purposes only. Longevity Costs is not a medical provider, pharmacy, or clinic, and should not be interpreted as medical advice, treatment guidance, or a claim that any therapy is safe, effective, or appropriate for you.

FAQ

Questions about ProLon vs Signos

Which provider looks stronger overall: ProLon or Signos?

ProLon currently scores better in the directory because of its blend of pricing visibility, service breadth, telehealth support, and clinic context. That does not mean it is automatically the best fit for every user.

Which provider is cheaper: ProLon or Signos?

ProLon has the lower visible starting price, but the real comparison still depends on membership requirements, labs, and service model.

What should buyers compare first?

Start with pricing model, service overlap, telehealth availability, lab-testing inclusion, and overall clinic structure before you click out to a provider.

Is ProLon worth it compared to Signos?

ProLon currently scores better in the directory based on pricing visibility, telehealth access, and service breadth. Whether it is worth it depends on your specific service need, geography, and how much friction you can tolerate in onboarding. Verify current pricing before deciding.

Can I cancel ProLon or Signos anytime?

ProLon: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling. Signos: Cancellation or pause terms were not clearly listed on the reviewed official pages and should be checked directly.

Related paths

Continue the comparison journey

ProLon review

Open the full provider page.

Signos review

Open the full provider page.

All providers

Browse the main directory.

Metabolic Health comparison

Open the service-specific head-to-head view.

Metabolic Health guide

Compare the broader treatment category.

Metabolic Health calculator

Estimate spend before choosing a provider.

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Methodology and disclaimer

Updated Apr 28, 2026

Comparison pages are generated from provider data, service overlap, price transparency signals, and editorial decision logic. The goal is to create a useful decision page, not a duplicate or thin SEO route.

Informational only. Longevity Costs publishes provider research, public pricing context, and comparison summaries for informational purposes only. The site is not a medical provider, clinic, pharmacy, or emergency service. Nothing on this page is medical advice, diagnosis, treatment guidance, or a claim that a therapy is proven, guaranteed, or appropriate for you. Consult a licensed medical professional before starting or changing any therapy.

Source

Public provider websites, rate sheets, and documented offers.

Verification

Verify final pricing directly with the provider before booking.

Cadence

Data is reviewed and updated on a rolling basis.

Sources

ProLon homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

ProLon faq page

Checked 2026-05-06 · Confidence 56%

FAQ reviewed for support, cancellation, and policy language.

Sources

Signos homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.