ProlongMD vs SynergenX for TRT (2026): Cost & Which Wins

Best for ProlongMD

Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.

Best for SynergenX

Users who want clinic-based hormone care with a path to at-home TRT.

Biggest difference

Remote-friendly vs Remote-friendly access model.

Decision helper

ProlongMD: ProlongMD shows a visible starting price of $169 per month, but deeper pricing detail is not fully public on the reviewed pages. SynergenX: SynergenX shows a visible starting price of $59 per month, but deeper pricing detail is not fully public on the reviewed pages.

Notable limitations

ProlongMD: Membership structure can make the first visible price look cleaner than the full long-term cost.

SynergenX: State footprint is meaningful but not truly nationwide.

Publicly verified care model notes

ProlongMD: The public flow suggests clinician review or consultation before treatment begins.

SynergenX: A mandatory consult step was not clearly listed on the reviewed homepage.

ProlongMD: Lab testing is signaled in the visible care model.

SynergenX: Lab testing is signaled in the visible care model.

ProlongMD: Cancellation or pause terms were not clearly listed on the reviewed official pages and should be checked directly.

SynergenX: No clear cancellation or refund language was surfaced on the reviewed official pages.

Transparency notes

ProlongMD: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

SynergenX: Payment, privacy, or billing-policy pages were reviewed, but insurance, HSA, or FSA handling should still be confirmed directly.

ProlongMD: Medication changes, shipping, or premium tiers may still change the final bill.

SynergenX: Medication changes, shipping, or premium tiers may still change the final bill.

Data snapshot — pricing sourced from public provider rates

Last updated

Apr 28, 2026

Providers analyzed

Price range

$169 vs $59

Methodology

How we collect data

Disclosure

Affiliate relationships

ProlongMD

Official website reviewed

telehealth hormone optimization clinic offering testosterone and longevity-focused treatment planning

ProlongMD is a telehealth hormone optimization clinic offering testosterone and longevity-focused treatment planning.

TRTWellness Labs

Starting price

$169

per month

Service availability

Telehealth available

Labs included

National telehealth

Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.

Visitors who want a longevity-oriented TRT comparison point without jumping to a concierge clinic.

See Pricing Details Check Provider

SynergenX

Specialist clinic

A large clinic-led hormone network combining in-person testing, self-inject TRT, and telehealth-supported follow-up.

SynergenX is a multi-location hormone clinic network offering in-clinic TRT, self-inject TRT, women's hormone therapy, peptide support, and ongoing lab follow-up.

TRTHRTPeptidesWellness Labs

Starting price

$59

per month

Service availability

Telehealth available

Labs included

65+ clinics nationwide

Users who want clinic-based hormone care with a path to at-home TRT.

Shoppers comparing traditional hormone clinics against telehealth membership brands.

See Pricing Details Check Provider

Signal	ProlongMD	SynergenX
TRT price	$169	$59
Price range	$169	$59
Care model	Remote-friendly	Remote-friendly
Membership model	Membership required	No membership required
Availability	21 states + telehealth	10 states + telehealth
Transparency score	5/5	5/5
Limitations	Membership structure can make the first visible price look cleaner than the full long-term cost.	State footprint is meaningful but not truly nationwide.

Winner by category

Best for price

SynergenX currently shows the lower visible trt price anchor.

Best for convenience

ProlongMD looks easier to use for shoppers prioritizing access and lower-friction logistics.

Best for service variety

SynergenX currently offers the broader service stack around this category.

Best for beginners

SynergenX looks friendlier for first-time shoppers who want simpler onboarding.

Which should you choose?

Choose SynergenX if your goal is the stronger overall mix of price clarity and service fit in trt. Choose ProlongMD if its access model or care structure is closer to how you actually want to buy this treatment.

Questions to ask before choosing

Specific to TRT programs — the service being compared here.

1Does the monthly price include medication only, or does it also cover consultations and lab monitoring?
2How frequently is lab work required, and what is the cost per panel if not included?
3Does the provider ship compounded testosterone, and which state pharmacy laws apply?
4What is the minimum commitment period before I can discontinue without penalty?

Shopper intent shortcuts

Cheapest likely scenario

SynergenX

SynergenX currently shows the lower visible trt price anchor, but the real bill still depends on labs, consults, and membership rules.

Fastest access

ProlongMD

ProlongMD looks better for low-friction access if you care most about telehealth and a simpler booking path.

Transparent pricing

ProlongMD

ProlongMD currently publishes the cleaner pricing trail for trt.

More medically supervised

Verify both directly

Both providers need direct verification on clinician review, labs, and follow-up cadence.

FAQ

TRT comparison questions

Which provider is cheaper for trt: ProlongMD or SynergenX?

SynergenX currently shows the lower visible trt price anchor, though the real comparison still depends on membership, labs, and consult structure.

Which provider looks stronger for trt overall?

SynergenX currently looks stronger on the service-specific comparison because of its current blend of pricing, access model, and overall provider fit.

Why break this out into a trt comparison page?

Because buyers often want a narrower answer than a full-provider comparison when they are only shopping one treatment category.

Related paths

Next comparison clicks

Full provider comparison

Zoom back out to the all-services comparison page.

ProlongMD TRT

Open the provider's service-specific review.

SynergenX TRT

Open the provider's service-specific review.

TRT guide

Compare the broader service category.

TRT calculator

Model likely spend for this category.

Regenics TRT

Compare another provider in this treatment category.

Defy Medical TRT

Compare another provider in this treatment category.

Next Health Membership Pricing Explained: What the Starting Price Does and Does Not Cover

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Function Health Membership Cost: What You Are Actually Paying For

Read related editorial context.

Methodology and disclaimer

Updated Apr 28, 2026

This service comparison page is generated from provider overlap, current price anchors, convenience signals, and treatment-specific fit data. It is designed to be useful for category research, not medical decision-making.

Informational only. Longevity Costs publishes provider research, public pricing context, and comparison summaries for informational purposes only. The site is not a medical provider, clinic, pharmacy, or emergency service. Nothing on this page is medical advice, diagnosis, treatment guidance, or a claim that a therapy is proven, guaranteed, or appropriate for you. Consult a licensed medical professional before starting or changing any therapy.

Source

Public provider websites, rate sheets, and documented offers.

Verification

Verify final pricing directly with the provider before booking.

Cadence

Data is reviewed and updated on a rolling basis.

Sources

ProlongMD homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

Sources

SynergenX homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

SynergenX contact page

Checked 2026-05-06 · Confidence 64%

Contact or support availability reviewed from official pages.

SynergenX faq page

Checked 2026-05-06 · Confidence 56%

FAQ reviewed for support, cancellation, and policy language.

SynergenX terms page

Checked 2026-05-06 · Confidence 50%

Terms or billing-policy language reviewed for cancellation clues.

SynergenX privacy page

Checked 2026-05-06 · Confidence 50%

Privacy or billing-policy page reviewed for support and payment context.

Publicly verified care model notes

ProlongMD: The public flow suggests clinician review or consultation before treatment begins.

SynergenX: A mandatory consult step was not clearly listed on the reviewed homepage.

ProlongMD: Lab testing is signaled in the visible care model.

SynergenX: Lab testing is signaled in the visible care model.

ProlongMD: Cancellation or pause terms were not clearly listed on the reviewed official pages and should be checked directly.

SynergenX: No clear cancellation or refund language was surfaced on the reviewed official pages.

Transparency notes

ProlongMD: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

SynergenX: Payment, privacy, or billing-policy pages were reviewed, but insurance, HSA, or FSA handling should still be confirmed directly.

ProlongMD: Medication changes, shipping, or premium tiers may still change the final bill.

SynergenX: Medication changes, shipping, or premium tiers may still change the final bill.

Signal

ProlongMD

SynergenX

TRT price

$169

$59

Price range

$169

$59

Care model

Remote-friendly

Membership model

Membership required

No membership required

Availability

21 states + telehealth

10 states + telehealth

Transparency score

5/5

Limitations

Membership structure can make the first visible price look cleaner than the full long-term cost.

State footprint is meaningful but not truly nationwide.

Winner by category

Best for price

SynergenX currently shows the lower visible trt price anchor.

Best for convenience

ProlongMD looks easier to use for shoppers prioritizing access and lower-friction logistics.

Best for service variety

SynergenX currently offers the broader service stack around this category.

Best for beginners

SynergenX looks friendlier for first-time shoppers who want simpler onboarding.

Questions to ask before choosing

Specific to TRT programs — the service being compared here.

1Does the monthly price include medication only, or does it also cover consultations and lab monitoring?

2How frequently is lab work required, and what is the cost per panel if not included?

3Does the provider ship compounded testosterone, and which state pharmacy laws apply?

4What is the minimum commitment period before I can discontinue without penalty?

Shopper intent shortcuts

Cheapest likely scenario

SynergenX

SynergenX currently shows the lower visible trt price anchor, but the real bill still depends on labs, consults, and membership rules.

Fastest access

ProlongMD

ProlongMD looks better for low-friction access if you care most about telehealth and a simpler booking path.

Transparent pricing

ProlongMD

ProlongMD currently publishes the cleaner pricing trail for trt.

More medically supervised

Verify both directly

Both providers need direct verification on clinician review, labs, and follow-up cadence.