Provider comparison1 shared servicesData confidence 64%

ProlongMD vs Upgrade Labs

ProlongMD and Upgrade Labs diverge most clearly on convenience: ProlongMD is remote-friendly, while Upgrade Labs is in-person. This page compares pricing, services, telehealth support, labs, and overall provider fit so it works as a real decision page instead of a thin comparison permutation.

Quick verdict

ProlongMD is the stronger current profile

ProlongMD has the stronger current profile for this comparison. Open it first — then verify pricing, labs, and cancellation terms directly before deciding.

ProlongMD: $169/per monthUpgrade Labs: $199/per packageUpdated: Apr 28, 2026

Open ProlongMD Open Upgrade Labs Get matched

Best for ProlongMD

Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.

Best for Upgrade Labs

Users who want a biohacking-club alternative to lab-only memberships.

Biggest difference

ProlongMD and Upgrade Labs diverge most clearly on convenience: ProlongMD is remote-friendly, while Upgrade Labs is in-person.

Price transparency: 5/5 vs 3/5. Availability: Remote-friendly vs In-person.

Market median

$153

86 researched providers in this treatment path.

Transparent pricing rate

97%

of researched providers publish a usable price anchor.

Telehealth rate

77%

support remote access in this comparison set.

Data snapshot — pricing sourced from public provider rates

Last updated

Apr 28, 2026

Providers analyzed

Price range

$169 vs $199

Methodology

How we collect data

Disclosure

Affiliate relationships

ProlongMD

Official website reviewed

telehealth hormone optimization clinic offering testosterone and longevity-focused treatment planning

ProlongMD is a telehealth hormone optimization clinic offering testosterone and longevity-focused treatment planning.

TRTWellness Labs

Starting price

$169

per month

Service availability

Telehealth available

Labs included

National telehealth

Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.

Visitors who want a longevity-oriented TRT comparison point without jumping to a concierge clinic.

See Pricing Details Check Provider

Upgrade Labs

Official website reviewed

biohacking and performance clinic brand with longevity-tech services and memberships

Upgrade Labs is a biohacking and performance clinic brand with longevity-tech services and memberships.

Wellness LabsDEXA ImagingSleep OptimizationLongevity Memberships

Starting price

$199

per package

Service availability

Clinic-led access

Labs may be separate

Santa Monica, CA

Users who want a biohacking-club alternative to lab-only memberships.

Shoppers comparing tech-forward wellness clubs in major metros.

See Pricing Details Check Provider

Signal	ProlongMD	Upgrade Labs
Starting price	$169 per month	$199 per package
Price range	$169	$199
Services offered	TRT, Wellness Labs	Wellness Labs, DEXA Imaging, Sleep Optimization, Longevity Memberships
Online vs in-person	Remote-friendly	In-person
Best for	Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.	Users who want a biohacking-club alternative to lab-only memberships.
Membership availability	Membership required	Membership required
Locations or availability	21 states + telehealth	Santa Monica, CA, Austin, TX
Transparency score	5/5	3/5
Limitations	Membership structure can make the first visible price look cleaner than the full long-term cost.	Membership structure can make the first visible price look cleaner than the full long-term cost.

Hidden fees to watch for

Published starting prices rarely include all costs. These are the most common fee gaps buyers miss when comparing ProlongMD and Upgrade Labs.

ProlongMD

Medication changes, shipping, or premium tiers may still change the final bill.

Upgrade Labs

Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Lab monitoring (both)

Most telehealth programs do not include lab work in the monthly fee. Expect $75–$150 per panel, required 2–4× per year for any hormone or TRT program.

Initiation and intake fees

Some providers charge a one-time intake fee ($50–$199) on top of the first monthly payment. This is not always visible on the pricing page.

ProlongMD pros and cons

Official site clearly positions ProlongMD around trt, wellness labs and broader longevity support.

Telehealth availability makes it easier to compare remote-care convenience against clinic-led alternatives.

Lab or diagnostics integration makes the total care model easier to compare than a headline price alone.

Membership structure can make the first visible price look cleaner than the full long-term cost.

Upgrade Labs pros and cons

Official site clearly positions Upgrade Labs around wellness labs and broader longevity support.

Physical or concierge delivery model adds useful contrast against telehealth-first providers already in the directory.

Published service framing is strong enough to support provider, comparison, and location pages.

Membership structure can make the first visible price look cleaner than the full long-term cost.

Notable limitations

ProlongMD: Membership structure can make the first visible price look cleaner than the full long-term cost.

Upgrade Labs: Membership structure can make the first visible price look cleaner than the full long-term cost.

Decision helper

ProlongMD has the cleaner current edge if you care most about transparency and a broader decision trail.

Upgrade Labs may still fit better if its geography, clinic structure, or narrower service mix is closer to what you want.

Both providers share Wellness Labs — compare pricing models for those specific services before deciding.

Best for

ProlongMD

Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.

Upgrade Labs

Users who want a biohacking-club alternative to lab-only memberships.

Winner by category

Best for price

ProlongMD currently shows the cleaner lower-cost starting point.

Best for convenience

ProlongMD currently looks easier to use for remote or low-friction access.

Best for service variety

Upgrade Labs offers the broader menu for users who may stack more than one treatment path.

Most cautious beginner

Start with ProlongMD if you want the simpler onboarding path before you compare the more complex alternative.

Best for beginners

ProlongMD looks friendlier for first-time shoppers who want simpler onboarding and less membership friction.

Questions to ask before choosing

These are specific to Wellness Labs programs — the primary service overlap between ProlongMD and Upgrade Labs.

1Is a physician order required, or can I order panels directly?
2Are results reviewed with a clinician, or returned raw with no interpretation?
3What is the cost per panel, and is a membership or bundle more cost-effective?
4Can I use insurance or my HSA/FSA to pay for any of these tests?

Which should you choose?

ProlongMD currently has the better comparison profile for this page, but that is not the same as a universal winner. Use ProlongMD as the first profile to open if you care most about clearer pricing and broader comparison detail. Use Upgrade Labs first if its access model or service style is closer to how you actually want to buy care.

Hidden-cost risk and cancellation

ProlongMD: Medication changes, shipping, or premium tiers may still change the final bill.

Upgrade Labs: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

ProlongMD: Cancellation or pause terms were not clearly listed on the reviewed official pages and should be checked directly.

Upgrade Labs: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling.

Intent-based shortcuts

I want the cheapest option

ProlongMD

ProlongMD currently shows the lower visible price anchor, but verify whether labs, medication, or membership fees sit outside the headline number.

I want fastest access

ProlongMD

ProlongMD looks easier to start quickly based on telehealth access, lower friction, or a simpler booking path.

I want stronger medical oversight

ProlongMD

ProlongMD publicly signals a stronger lab-driven process, which can matter more than the cheapest starting price.

I want transparent pricing

ProlongMD

ProlongMD currently publishes the cleaner pricing trail, but both still deserve a final check on renewals and add-on fees.

I want local or in-person care

Upgrade Labs

Use clinic footprint, state coverage, and intake model together here - local care usually changes convenience, follow-up cadence, and total cost.

Publicly verified differences

ProlongMD: Users comparing mid-market online TRT programs that still emphasize physician review and lab structure.

Upgrade Labs: Users who want a biohacking-club alternative to lab-only memberships.

ProlongMD: ProlongMD shows a visible starting price of $169 per month, but deeper pricing detail is not fully public on the reviewed pages.

Upgrade Labs: Upgrade Labs shows a visible starting price of $199 per package, but deeper pricing detail is not fully public on the reviewed pages.

ProlongMD: A recurring membership or subscription appears to be part of the offer, but the exact public fee still needs manual review.

Upgrade Labs: A recurring membership or subscription appears to be part of the offer, but the exact public fee still needs manual review.

ProlongMD: The public flow suggests clinician review or consultation before treatment begins.

Upgrade Labs: A mandatory consult step was not clearly listed on the reviewed homepage.

Transparency and policy notes

ProlongMD: Insurance, HSA, or FSA handling was not fully verified from the reviewed official pages.

Upgrade Labs: Payment, privacy, or billing-policy pages were reviewed, but insurance, HSA, or FSA handling should still be confirmed directly.

ProlongMD: Medication changes, shipping, or premium tiers may still change the final bill.

Upgrade Labs: Labs, medication fulfillment, consults, or shipping may sit outside the headline price.

Some outbound buttons may use affiliate relationships. Rankings are driven by editorial methodology and provider data, not by paid placement. This directory is for informational and research purposes only. Longevity Costs is not a medical provider, pharmacy, or clinic, and should not be interpreted as medical advice, treatment guidance, or a claim that any therapy is safe, effective, or appropriate for you.

FAQ

Questions about ProlongMD vs Upgrade Labs

Which provider looks stronger overall: ProlongMD or Upgrade Labs?

ProlongMD currently scores better in the directory because of its blend of pricing visibility, service breadth, telehealth support, and clinic context. That does not mean it is automatically the best fit for every user.

Which provider is cheaper: ProlongMD or Upgrade Labs?

ProlongMD has the lower visible starting price, but the real comparison still depends on membership requirements, labs, and service model.

What should buyers compare first?

Start with pricing model, service overlap, telehealth availability, lab-testing inclusion, and overall clinic structure before you click out to a provider.

Is ProlongMD worth it compared to Upgrade Labs?

ProlongMD currently scores better in the directory based on pricing visibility, telehealth access, and service breadth. Whether it is worth it depends on your specific service need, geography, and how much friction you can tolerate in onboarding. Verify current pricing before deciding.

Can I cancel ProlongMD or Upgrade Labs anytime?

ProlongMD: Cancellation or pause terms were not clearly listed on the reviewed official pages and should be checked directly. Upgrade Labs: Official policy pages reference cancellation, refund, or renewal terms, but buyers should still verify the exact current policy before enrolling.

Related paths

Continue the comparison journey

ProlongMD review

Open the full provider page.

Upgrade Labs review

Open the full provider page.

All providers

Browse the main directory.

Wellness Labs comparison

Open the service-specific head-to-head view.

Wellness Labs guide

Compare the broader treatment category.

Wellness Labs calculator

Estimate spend before choosing a provider.

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Methodology and disclaimer

Updated Apr 28, 2026

Comparison pages are generated from provider data, service overlap, price transparency signals, and editorial decision logic. The goal is to create a useful decision page, not a duplicate or thin SEO route.

Informational only. Longevity Costs publishes provider research, public pricing context, and comparison summaries for informational purposes only. The site is not a medical provider, clinic, pharmacy, or emergency service. Nothing on this page is medical advice, diagnosis, treatment guidance, or a claim that a therapy is proven, guaranteed, or appropriate for you. Consult a licensed medical professional before starting or changing any therapy.

Source

Public provider websites, rate sheets, and documented offers.

Verification

Verify final pricing directly with the provider before booking.

Cadence

Data is reviewed and updated on a rolling basis.

Sources

ProlongMD homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

Sources

Upgrade Labs homepage

Checked 2026-05-06 · Confidence 68%

Official homepage reviewed for care model and visible public positioning.

Upgrade Labs contact page

Checked 2026-05-06 · Confidence 64%

Contact or support availability reviewed from official pages.

Upgrade Labs faq page

Checked 2026-05-06 · Confidence 56%

FAQ reviewed for support, cancellation, and policy language.

Upgrade Labs terms page

Checked 2026-05-06 · Confidence 62%

Terms or billing-policy language reviewed for cancellation clues.

Upgrade Labs privacy page

Checked 2026-05-06 · Confidence 50%

Privacy or billing-policy page reviewed for support and payment context.